Reference ranges for the fetal cardiac circumference derived by cardio-spatiotemporal image correlation from 14 to 40 weeks' gestation
Objectives-The purpose of this study was to construct reference ranges for the fetal cardiac circumference derived from volume data sets obtained by cardio-spatiotemporal image correlation. Methods-A prospective descriptive study was conducted on normal singleton pregnancies with certain dates from...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
2014
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Online Access: | http://www.ncbi.nlm.nih.gov/pubmed/3502482 http://www.scopus.com/inward/record.url?eid=2-s2.0-80052484167&partnerID=40&md5=7718aaceb171d908b50ba207a9963eb2 http://cmuir.cmu.ac.th/handle/6653943832/3081 |
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Institution: | Chiang Mai University |
Language: | English |
Summary: | Objectives-The purpose of this study was to construct reference ranges for the fetal cardiac circumference derived from volume data sets obtained by cardio-spatiotemporal image correlation. Methods-A prospective descriptive study was conducted on normal singleton pregnancies with certain dates from 14 to 40 weeks' gestation. All underwent cardio- spatiotemporal image correlation to acquire volume data sets for subsequent analysis. Cardiac circumferences were measured offline in a multiplanar view with 4-dimensional imaging software. The reference ranges were constructed against gestational weeks and the biparietal diameter as independent variables, using regression models for both the mean and SD. Results-A total of 678 satisfactory volumes were analyzed. Normal reference ranges for predicting means and SDs of the fetal cardiac circumference were established based on best-fitted equations. The mean cardiac circumference (millimeters) was modeled as a function of gestational age (weeks) and biparietal diameter (centimeters) as follows: cardiac circumference = -53.11 + 6.56 × gestational age - 0.035 × gestational age2 (SD = 0.67 + 0.18 × gestational age) and -17.60 + 17.68 × biparietal diameter (SD = 1.651 + 0.61 × biparietal diameter). Equations for z score calculation were also provided, and percentile charts for predicting the cardiac circumference at various points of gestational age and biparietal diameter were constructed. Conclusions-Normal reference ranges and z scores for the fetal cardiac circumference have been provided. These normative data may be useful tools for assessment of fetal cardiac size, especially in cardiomegaly due to fetal anemia. © 2011 by the American Institute of Ultrasound in Medicine. |
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