Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes

Bioactive compounds [ferulic acid (F), γ-oryzanol (O) and phytic acid (P)] in rice bran have been widely used as antioxidants in skin care products. However, one of the major problems of antioxidants is the deterioration of their activities during long exposure to air and light. Niosomes have been u...

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Main Authors: Manosroi A., Chutoprapat R., Sato Y., Miyamoto K., Hsueh K., Abe M., Manosroi W., Manosroi J.
Format: Conference or Workshop Item
Language:English
Published: 2014
Online Access:http://www.ncbi.nlm.nih.gov/pubmed/3502482
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-30912014-08-30T02:25:45Z Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes Manosroi A. Chutoprapat R. Sato Y. Miyamoto K. Hsueh K. Abe M. Manosroi W. Manosroi J. Bioactive compounds [ferulic acid (F), γ-oryzanol (O) and phytic acid (P)] in rice bran have been widely used as antioxidants in skin care products. However, one of the major problems of antioxidants is the deterioration of their activities during long exposure to air and light. Niosomes have been used to entrap many degradable active agents not only for stability improvement, but also for increasing skin hydration. The objective of this study was to determine antioxidant activities [by in vitro ORAC (oxygen radical absorbance capacity) and ex vivo lipid peroxidation inhibition assay] and in vivo human skin hydration effects of gel and cream containing the rice bran extracts entrapped in niosomes. Gel and cream containing the rice bran extracts entrapped in niosomes showed higher antioxidant activity (ORAC value) at 20-28 μmol of Trolox equivalents (TE) per gram of the sample than the placebo gel and cream which gave 16-18 μmolTE/g. Human sebum treated with these formulations showed more lipid peroxidation inhibition activity than with no treatment of about 1.5 times. The three different independent techniques including corneometer, vapometer and confocal Raman microspectroscopy (CRM) indicated the same trend in human skin hydration enhancement of the gel or cream formulations containing the rice bran extracts entrapped in niosomes of about 20, 3 and 30%, respectively. This study has demonstrated the antioxidant activities and skin hydration enhancement of the rice bran bioactive compounds when entrapped in niosomes and incorporated in cream formulations. © 2011 American Scientific Publishers. 2014-08-30T02:25:45Z 2014-08-30T02:25:45Z 2011 Conference Paper 15334880 10.1166/jnn.2011.3532 http://www.ncbi.nlm.nih.gov/pubmed/3502482 http://www.scopus.com/inward/record.url?eid=2-s2.0-79955873936&partnerID=40&md5=8c811c7cdca04210be6f0bb589a0196e http://cmuir.cmu.ac.th/handle/6653943832/3091 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description Bioactive compounds [ferulic acid (F), γ-oryzanol (O) and phytic acid (P)] in rice bran have been widely used as antioxidants in skin care products. However, one of the major problems of antioxidants is the deterioration of their activities during long exposure to air and light. Niosomes have been used to entrap many degradable active agents not only for stability improvement, but also for increasing skin hydration. The objective of this study was to determine antioxidant activities [by in vitro ORAC (oxygen radical absorbance capacity) and ex vivo lipid peroxidation inhibition assay] and in vivo human skin hydration effects of gel and cream containing the rice bran extracts entrapped in niosomes. Gel and cream containing the rice bran extracts entrapped in niosomes showed higher antioxidant activity (ORAC value) at 20-28 μmol of Trolox equivalents (TE) per gram of the sample than the placebo gel and cream which gave 16-18 μmolTE/g. Human sebum treated with these formulations showed more lipid peroxidation inhibition activity than with no treatment of about 1.5 times. The three different independent techniques including corneometer, vapometer and confocal Raman microspectroscopy (CRM) indicated the same trend in human skin hydration enhancement of the gel or cream formulations containing the rice bran extracts entrapped in niosomes of about 20, 3 and 30%, respectively. This study has demonstrated the antioxidant activities and skin hydration enhancement of the rice bran bioactive compounds when entrapped in niosomes and incorporated in cream formulations. © 2011 American Scientific Publishers.
format Conference or Workshop Item
author Manosroi A.
Chutoprapat R.
Sato Y.
Miyamoto K.
Hsueh K.
Abe M.
Manosroi W.
Manosroi J.
spellingShingle Manosroi A.
Chutoprapat R.
Sato Y.
Miyamoto K.
Hsueh K.
Abe M.
Manosroi W.
Manosroi J.
Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes
author_facet Manosroi A.
Chutoprapat R.
Sato Y.
Miyamoto K.
Hsueh K.
Abe M.
Manosroi W.
Manosroi J.
author_sort Manosroi A.
title Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes
title_short Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes
title_full Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes
title_fullStr Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes
title_full_unstemmed Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes
title_sort antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes
publishDate 2014
url http://www.ncbi.nlm.nih.gov/pubmed/3502482
http://www.scopus.com/inward/record.url?eid=2-s2.0-79955873936&partnerID=40&md5=8c811c7cdca04210be6f0bb589a0196e
http://cmuir.cmu.ac.th/handle/6653943832/3091
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