Curcuminoids purified from turmeric powder modulate the function of human multidrug resistance protein 1 (ABCC1)

Multidrug resistance is a major cause of chemotherapy failure in cancer patients. One of the resistance mechanisms is the overexpression of drug efflux pumps such as P-glycoprotein and multidrug resistance protein 1 (MRP1, (ABCC1)). In this study, curcumin mixture and three major curcuminoids purifi...

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Bibliographic Details
Main Authors: Chearwae W., Wu CP., Chu HY., Lee TR., Ambudkar SV., Limtrakul P.
Format: Comparative Study
Language:English
Published: 2014
Online Access:http://www.ncbi.nlm.nih.gov/pubmed/3502482
http://cmuir.cmu.ac.th/handle/6653943832/3232
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Institution: Chiang Mai University
Language: English