The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz

Pharmacological studies were conducted with the hexane extract of the dry stem of Diospyros variegata Kruz. (Ebenaceae) on experimental animals for evaluating the analgesic, antipyretic and anti-inflammatory activities. In the analgesic test, the hexane extract elicited inhibitory intensity on aceti...

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Main Authors: Trongsakul S., Panthong A., Kanjanapothi D., Taesotikul T.
Format: Article
Language:English
Published: 2014
Online Access:http://www.ncbi.nlm.nih.gov/pubmed/3502482
http://cmuir.cmu.ac.th/handle/6653943832/3261
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-32612014-08-30T02:25:56Z The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz Trongsakul S. Panthong A. Kanjanapothi D. Taesotikul T. Pharmacological studies were conducted with the hexane extract of the dry stem of Diospyros variegata Kruz. (Ebenaceae) on experimental animals for evaluating the analgesic, antipyretic and anti-inflammatory activities. In the analgesic test, the hexane extract elicited inhibitory intensity on acetic acid-induced writhing response and on the late phase of formalin test but possessed only a weak effect on the tail-flick response and on the early phase of formalin test. The hexane extract also elicited antipyretic action when tested in yeast-induced hyperthermia in rats. In addition, the hexane extract showed an anti-inflammatory effect when tested in ethyl phenylpropiolate (EPP)- and arachidonic acid (AA)-induced rat ear edema. 2014-08-30T02:25:56Z 2014-08-30T02:25:56Z 2003 Journal Article 0378-8741 12639744 http://www.ncbi.nlm.nih.gov/pubmed/3502482 http://cmuir.cmu.ac.th/handle/6653943832/3261 eng
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description Pharmacological studies were conducted with the hexane extract of the dry stem of Diospyros variegata Kruz. (Ebenaceae) on experimental animals for evaluating the analgesic, antipyretic and anti-inflammatory activities. In the analgesic test, the hexane extract elicited inhibitory intensity on acetic acid-induced writhing response and on the late phase of formalin test but possessed only a weak effect on the tail-flick response and on the early phase of formalin test. The hexane extract also elicited antipyretic action when tested in yeast-induced hyperthermia in rats. In addition, the hexane extract showed an anti-inflammatory effect when tested in ethyl phenylpropiolate (EPP)- and arachidonic acid (AA)-induced rat ear edema.
format Article
author Trongsakul S.
Panthong A.
Kanjanapothi D.
Taesotikul T.
spellingShingle Trongsakul S.
Panthong A.
Kanjanapothi D.
Taesotikul T.
The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz
author_facet Trongsakul S.
Panthong A.
Kanjanapothi D.
Taesotikul T.
author_sort Trongsakul S.
title The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz
title_short The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz
title_full The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz
title_fullStr The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz
title_full_unstemmed The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz
title_sort analgesic, antipyretic and anti-inflammatory activity of diospyros variegata kruz
publishDate 2014
url http://www.ncbi.nlm.nih.gov/pubmed/3502482
http://cmuir.cmu.ac.th/handle/6653943832/3261
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