Gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node

Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30 female) used were aged ranging from 1-day- to 30-year-old. The elements were analyzed using an inductive...

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Main Authors: Satoh H., Tohno S., Minami T., Oishi T., Hayashi M., Tohno Y.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-78649370212&partnerID=40&md5=1356245e810579dea1eb04ab9aa05b75
http://cmuir.cmu.ac.th/handle/6653943832/3627
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-36272014-08-30T02:35:08Z Gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node Satoh H. Tohno S. Minami T. Oishi T. Hayashi M. Tohno Y. Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30 female) used were aged ranging from 1-day- to 30-year-old. The elements were analyzed using an inductively coupled plasma-atomic emission spectrometer (ICP-AES). Advancing age decreased all the trace elements. Ca, P, S and Mg significantly decreased. The correlation coefficients of Ca and P were -0.178±0.081 (p<0.05) and -0.088±0.022 (p<0.05) in male (n=30), and -0.095±0.026 (p<0.05) and -0.069±0.017 (p<0.05) in female (n=30), respectively. The age-dependent coefficients for Fe/Ca, Zn/Ca, Fe/P, Fe/S, Zn/S, Fe/Mg and Zn/Mg were exhibited markedly in male, but all was less in female. In gender-related differences, only a ratio of P/Ca (p<0.05) was significantly observed with ageing. The trace elements such as Cu, Se and Sn were less detected in the SA nodes. These results indicate that the age-dependent changes in the ratios of elements are appeared more rapidly in male monkey SA node, and the gender difference is observed in ratio of P/Ca. The different attenuations may be involved with the age- and gender-related SA nodal functions. 2014-08-30T02:35:08Z 2014-08-30T02:35:08Z 2010 Article 12264512 10.4196/kjpp.2010.14.5.249 KJPPF http://www.scopus.com/inward/record.url?eid=2-s2.0-78649370212&partnerID=40&md5=1356245e810579dea1eb04ab9aa05b75 http://cmuir.cmu.ac.th/handle/6653943832/3627 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30 female) used were aged ranging from 1-day- to 30-year-old. The elements were analyzed using an inductively coupled plasma-atomic emission spectrometer (ICP-AES). Advancing age decreased all the trace elements. Ca, P, S and Mg significantly decreased. The correlation coefficients of Ca and P were -0.178±0.081 (p<0.05) and -0.088±0.022 (p<0.05) in male (n=30), and -0.095±0.026 (p<0.05) and -0.069±0.017 (p<0.05) in female (n=30), respectively. The age-dependent coefficients for Fe/Ca, Zn/Ca, Fe/P, Fe/S, Zn/S, Fe/Mg and Zn/Mg were exhibited markedly in male, but all was less in female. In gender-related differences, only a ratio of P/Ca (p<0.05) was significantly observed with ageing. The trace elements such as Cu, Se and Sn were less detected in the SA nodes. These results indicate that the age-dependent changes in the ratios of elements are appeared more rapidly in male monkey SA node, and the gender difference is observed in ratio of P/Ca. The different attenuations may be involved with the age- and gender-related SA nodal functions.
format Article
author Satoh H.
Tohno S.
Minami T.
Oishi T.
Hayashi M.
Tohno Y.
spellingShingle Satoh H.
Tohno S.
Minami T.
Oishi T.
Hayashi M.
Tohno Y.
Gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node
author_facet Satoh H.
Tohno S.
Minami T.
Oishi T.
Hayashi M.
Tohno Y.
author_sort Satoh H.
title Gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node
title_short Gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node
title_full Gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node
title_fullStr Gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node
title_full_unstemmed Gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node
title_sort gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-78649370212&partnerID=40&md5=1356245e810579dea1eb04ab9aa05b75
http://cmuir.cmu.ac.th/handle/6653943832/3627
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