Versican facilitates chondrocyte differentiation and regulates joint morphogenesis

• Main Authors: Choocheep K., Hatano S., Takagi H., Watanabe H., Kimata K., Kongtawelert P.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-77954225772&partnerID=40&md5=04bbabbe991cc72081072885f69d006f; http://cmuir.cmu.ac.th/handle/6653943832/3645
• Institution: Chiang Mai University

Versican/PG-M is a large chondroitin sulfate proteoglycan in the extracellular matrix, which is transiently expressed in mesenchymal condensation areas during tissue morphogenesis. Here, we generated versican conditional knock-out mice Prx1-Cre/Vcanflox/flox, in which Vcan is pruned out by site-spec...