Comparative study between chitin/polyacrylic acid (paa) dressing, lipido-colloid absorbent dressing and alginate wound dressing: A pilot study in the treatment of partial-thickness wound

• Main Authors: Angspatt A., Tanvatcharaphan P., Channasanon S., Tanodekaew S., Chokrungvaranont P., Sirimaharaj W.
• Format: Article
• Language: English; Thai
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-77954518309&partnerID=40&md5=32a7fa174225d131694568546099f179; http://cmuir.cmu.ac.th/handle/6653943832/3662
• Institution: Chiang Mai University

Background: Polyacrylic acid grafted chitin (Chitin-PAA) contains a hydrogel characteristic that makes it more suitable for wound dressing application. In animal models, Chitin-PAA dressing exhibited properties as a promising dressing. Epithelization promotion, rapid reduction of wound size, reduction of inflammatory cell response, and less toxicity had been noted. Objective: Carryout a pilot clinical comparative study of Chitin-PAA dressing, lipido-colloid absorbent dressing, and alginate wound dressing in the treatment of partial-thickness wound. Material and Method: Between June 2006 and March 2007, 36 partial-thickness wounds were randomized into three groups and three different types of dressing were used. Each wound was treated until it was completely healed, and a visual analogue scale was used for the pain evaluation. Result: The present study shows the visual analogue pain score in the Chitin-PAA group seems to be a bit higher than the Urgocell® group but not statistically different. The completely healed day is not significantly different. Three patients in the lipido-colloid absorbent dressing groups had wound infection but eventually healed after treatment. Conclusion: There was no statistical difference in terms of visual analogue pain score and healing time between the lipido- colloid absorbent dressing, alginate dressing, and chitin-PAA dressing.