Pharmacokinetics and safety of a new paediatric fixed-dose combination of zidovudine/lamivudine/nevirapine in HIV-infected children

• Main Authors: Chokephaibulkit K., Cressey T.R., Capparelli E., Sirisanthana V., Muresan P., Hongsiriwon S., Ngampiyaskul C., Limwongse C., Wittawatmongkol O., Aurpibul L., Kabat B., Toye M., Smith M.E., Eksaengsri A., McIntosh K., Yogev R.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-83455163806&partnerID=40&md5=5125d187f76c91d165d7c502e0cd1a0d; http://cmuir.cmu.ac.th/handle/6653943832/3697
• Institution: Chiang Mai University

Background: Alternatives to the available stavudine-containing paediatric fixed-dose combination (FDC) tablets are rapidly needed due to concerns regarding the cumulative toxicity of long-term stavudine exposure. We report the bioavailability and short-term safety of a novel paediatric FDC tablet of...