Rapid diagnosis of trisomy 21 by relative gene copy using real-time quantitative polymerase chain reaction

• Main Authors: Sanguansermsri C., Tanpaiboon P., Charoenkwan P., Phusua A., Sanguansermsri T.
• Format: Article
• Language: English
• Published: Asian Biomedicine 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84908039772&partnerID=40&md5=fbf51c0903ed506a63c5d3dfcb3c6311; http://cmuir.cmu.ac.th/handle/6653943832/37624
• Institution: Chiang Mai University

Background: Trisomy 21 or Down syndrome (DS) is the most common aneuploidy disorder. Fetal karyotypic analysis remains the criterion standard for prenatal diagnosis of DS, although the method is time consuming and requires skilled personnel. Real-time quantitative polymerase chain reaction (qPCR) ca...