Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa

Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa

A phytochemical investigation of the acetone extract from the immature fruits of Garcinia cowa led to the isolation of two novel tetraoxygenated xanthones, garcicowanones A (1) and B (2), together with eight known tetraoxygeanted xanthones. Their structures were determined by spectroscopic analysis....

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Main Authors: Auranwiwat C., Trisuwan K., Saiai A., Pyne S.G., Ritthiwigrom T.
Format: Article
Language:English
Published: Elsevier 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84907346833&partnerID=40&md5=7abaac6e73339c4cab01f0e3d062e620
http://cmuir.cmu.ac.th/handle/6653943832/37650
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-376502014-12-09T05:56:29Z Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa Auranwiwat C. Trisuwan K. Saiai A. Pyne S.G. Ritthiwigrom T. A phytochemical investigation of the acetone extract from the immature fruits of Garcinia cowa led to the isolation of two novel tetraoxygenated xanthones, garcicowanones A (1) and B (2), together with eight known tetraoxygeanted xanthones. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their antibacterial activity against Bacillus cereus TISTR 688, Bacillus subtilis TISTR 008, Micrococcus luteus TISTR 884, Staphylococcus aureus TISTR 1466, Escherichia coli TISTR 780, Pseudomonas aeruginosa TISTR 781, Salmonella typhimurium TISTR 292 and Staphylococcus epidermidis ATCC 12228. α-Mangostin showed potent activity (MIC 0.25-1 μg/mL) against three Gram-positive strains and garcicowanone A and β-mangostin exhibited strong antibacterial activity against B. cereus with the same MIC values of 0.25 μg/mL. © 2014 Elsevier B.V. All rights reserved. 2014-12-09T05:56:29Z 2014-12-09T05:56:29Z 2014 Article 0367326X 10.1016/j.fitote.2014.08.003 FTRPA http://www.scopus.com/inward/record.url?eid=2-s2.0-84907346833&partnerID=40&md5=7abaac6e73339c4cab01f0e3d062e620 http://cmuir.cmu.ac.th/handle/6653943832/37650 English Elsevier
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description A phytochemical investigation of the acetone extract from the immature fruits of Garcinia cowa led to the isolation of two novel tetraoxygenated xanthones, garcicowanones A (1) and B (2), together with eight known tetraoxygeanted xanthones. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their antibacterial activity against Bacillus cereus TISTR 688, Bacillus subtilis TISTR 008, Micrococcus luteus TISTR 884, Staphylococcus aureus TISTR 1466, Escherichia coli TISTR 780, Pseudomonas aeruginosa TISTR 781, Salmonella typhimurium TISTR 292 and Staphylococcus epidermidis ATCC 12228. α-Mangostin showed potent activity (MIC 0.25-1 μg/mL) against three Gram-positive strains and garcicowanone A and β-mangostin exhibited strong antibacterial activity against B. cereus with the same MIC values of 0.25 μg/mL. © 2014 Elsevier B.V. All rights reserved.
format Article
author Auranwiwat C.
Trisuwan K.
Saiai A.
Pyne S.G.
Ritthiwigrom T.
spellingShingle Auranwiwat C.
Trisuwan K.
Saiai A.
Pyne S.G.
Ritthiwigrom T.
Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
author_facet Auranwiwat C.
Trisuwan K.
Saiai A.
Pyne S.G.
Ritthiwigrom T.
author_sort Auranwiwat C.
title Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_short Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_full Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_fullStr Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_full_unstemmed Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_sort antibacterial tetraoxygenated xanthones from the immature fruits of garcinia cowa
publisher Elsevier
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-84907346833&partnerID=40&md5=7abaac6e73339c4cab01f0e3d062e620
http://cmuir.cmu.ac.th/handle/6653943832/37650
_version_ 1681421385393504256

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