Cucurbitacin B causes increased radiation sensitivity of human breast cancer cells via G2/M cell cycle arrest

• Main Authors: Duangmano,S., Sae-Lim,P., Suksamrarn,A., Patmasiriwat,P., Domann,F.E.
• Format: Article
• Published: Hindawi Publishing Corporation 2015
• Subjects: Oncology
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84862280414&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38103
• Institution: Chiang Mai University

Purpose. To explore the effects of cucurbitacin B on the radiation survival of human breast cancer cells and to elucidate the cellular mechanism of radiosensitization if any. Materials and Methods. Human breast carcinoma cell lines were treated with cucurbitacin B before irradiation with 0-10Gy of 1...