Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation

• Main Authors: Duangmano,S., Sae-Lim,P., Suksamrarn,A., Domann,F.E., Patmasiriwat,P.
• Format: Article
• Published: BioMed Central 2015
• Subjects: Complementary and Alternative Medicine
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84867308614&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38106
• Institution: Chiang Mai University

Background: Cucurbitacin B, an oxygenated tetracyclic triterpenoid compound extracted from the Thai medicinal plant Trichosanthes cucumerina L., has been reported to have several biological activities including anti-inflammatory, antimicrobial and anticancer. Cucurbitacin B is great of interest beca...