Effect of serotonin depletion on cortical spreading depression evoked cerebrovascular changes

• Main Authors: Maneesri,S., Supornsilpchai,W., Saengjaroentham,C., Pleumsamran,J., Srikiatkhachorn,A.
• Format: Article
• Published: IOS Press 2015
• Subjects: Medicine (all); Biochemistry, Genetics and Molecular Biology (all)
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84871682334&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38237
• Institution: Chiang Mai University

Background: The cortical spreading depression (CSD) is a phenomenon associated with several pathological conditions including migraine. It can induce alterations in both neural and vascular compartments. Serotonin (5-HT) depletion is known as a condition involved in migraine pathophysiology. The hyp...