Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (TGF-β)-snail signaling axis

© 2014 by The American Society for Biochemistry and Molecular Biology, Inc. Background: Hyaluronan overproduction is implicated in breast cancer progression. Results: Hyaluronan overproduction expands cancer stem-like cells through the up-regulation of Snail and Twist expression. Conclusion: Hyaluro...

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Main Authors:	Chanmee,T., Ontong,P., Mochizuki,N., Kongtawelert,P., Konno,K., Itano,N.
Format:	Article
Published:	American Society for Biochemistry and Molecular Biology Inc. 2015
Subjects:	Cell Biology Molecular Biology Biochemistry
Online Access:	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84907270573&origin=inward http://cmuir.cmu.ac.th/handle/6653943832/38307
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-38307
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spelling	th-cmuir.6653943832-383072015-06-16T07:46:54Z Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (TGF-β)-snail signaling axis Chanmee,T. Ontong,P. Mochizuki,N. Kongtawelert,P. Konno,K. Itano,N. Cell Biology Molecular Biology Biochemistry © 2014 by The American Society for Biochemistry and Molecular Biology, Inc. Background: Hyaluronan overproduction is implicated in breast cancer progression. Results: Hyaluronan overproduction expands cancer stem-like cells through the up-regulation of Snail and Twist expression. Conclusion: Hyaluronan overproduction allows plastic cancer cells to revert to stem cell states via Twist and the transforming growth factor β-Snail signaling axis. Significance: These findings will help to understand the unique hyaluronan-dependent mechanisms that govern cancer cell plasticity and cancer stem cell expansion. 2015-06-16T07:46:54Z 2015-06-16T07:46:54Z 2014-09-19 Article 00219258 2-s2.0-84907270573 10.1074/jbc.M114.564120 25077968 http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84907270573&origin=inward http://cmuir.cmu.ac.th/handle/6653943832/38307 American Society for Biochemistry and Molecular Biology Inc.
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Cell Biology Molecular Biology Biochemistry
spellingShingle	Cell Biology Molecular Biology Biochemistry Chanmee,T. Ontong,P. Mochizuki,N. Kongtawelert,P. Konno,K. Itano,N. Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (TGF-β)-snail signaling axis
description	© 2014 by The American Society for Biochemistry and Molecular Biology, Inc. Background: Hyaluronan overproduction is implicated in breast cancer progression. Results: Hyaluronan overproduction expands cancer stem-like cells through the up-regulation of Snail and Twist expression. Conclusion: Hyaluronan overproduction allows plastic cancer cells to revert to stem cell states via Twist and the transforming growth factor β-Snail signaling axis. Significance: These findings will help to understand the unique hyaluronan-dependent mechanisms that govern cancer cell plasticity and cancer stem cell expansion.
format	Article
author	Chanmee,T. Ontong,P. Mochizuki,N. Kongtawelert,P. Konno,K. Itano,N.
author_facet	Chanmee,T. Ontong,P. Mochizuki,N. Kongtawelert,P. Konno,K. Itano,N.
author_sort	Chanmee,T.
title	Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (TGF-β)-snail signaling axis
title_short	Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (TGF-β)-snail signaling axis
title_full	Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (TGF-β)-snail signaling axis
title_fullStr	Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (TGF-β)-snail signaling axis
title_full_unstemmed	Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (TGF-β)-snail signaling axis
title_sort	excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (tgf-β)-snail signaling axis
publisher	American Society for Biochemistry and Molecular Biology Inc.
publishDate	2015
url	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84907270573&origin=inward http://cmuir.cmu.ac.th/handle/6653943832/38307
_version_	1681421449912385536

Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of twist and the transforming growth factor β (TGF-β)-snail signaling axis

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