Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities

A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data....

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Main Authors:	Nayyatip S., Thaichana P., Buayairaksa M., Tuntiwechapikul W., Meepowpan P., Nuntasaen N., Pompimon W.
Format:	Article
Language:	English
Published:	2014
Online Access:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84860116503&partnerID=40&md5=a045402327748bdd86971e6e733f3293 http://www.ncbi.nlm.nih.gov/pubmed/22606026 http://cmuir.cmu.ac.th/handle/6653943832/3833
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Institution:	Chiang Mai University
Language:	English

id	th-cmuir.6653943832-3833
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spelling	th-cmuir.6653943832-38332014-08-30T02:35:22Z Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities Nayyatip S. Thaichana P. Buayairaksa M. Tuntiwechapikul W. Meepowpan P. Nuntasaen N. Pompimon W. A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively. © 2012 by the authors. 2014-08-30T02:35:22Z 2014-08-30T02:35:22Z 2012 Article 14220067 10.3390/ijms13045010 http://www.scopus.com/inward/record.url?eid=2-s2.0-84860116503&partnerID=40&md5=a045402327748bdd86971e6e733f3293 http://www.ncbi.nlm.nih.gov/pubmed/22606026 http://cmuir.cmu.ac.th/handle/6653943832/3833 English
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
language	English
description	A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively. © 2012 by the authors.
format	Article
author	Nayyatip S. Thaichana P. Buayairaksa M. Tuntiwechapikul W. Meepowpan P. Nuntasaen N. Pompimon W.
spellingShingle	Nayyatip S. Thaichana P. Buayairaksa M. Tuntiwechapikul W. Meepowpan P. Nuntasaen N. Pompimon W. Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
author_facet	Nayyatip S. Thaichana P. Buayairaksa M. Tuntiwechapikul W. Meepowpan P. Nuntasaen N. Pompimon W.
author_sort	Nayyatip S.
title	Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_short	Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_full	Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_fullStr	Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_full_unstemmed	Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_sort	aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
publishDate	2014
url	http://www.scopus.com/inward/record.url?eid=2-s2.0-84860116503&partnerID=40&md5=a045402327748bdd86971e6e733f3293 http://www.ncbi.nlm.nih.gov/pubmed/22606026 http://cmuir.cmu.ac.th/handle/6653943832/3833
_version_	1681420123208941568

Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities

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