Vagus nerve stimulation initiated late during ischemia, but not reperfusion, exerts cardioprotection via amelioration of cardiac mitochondrial dysfunction

• Main Authors: Shinlapawittayatorn,K., Chinda,K., Palee,S., Surinkaew,S., Kumfu,S., Kumphune,S., Chattipakorn,S.C., KenKnight,B.H., Chattipakorn,N.
• Format: Article
• Published: Elsevier 2015
• Subjects: Cardiology and Cardiovascular Medicine; Physiology (medical)
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84919383950&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38354
• Institution: Chiang Mai University

© 2014 Heart Rhythm Society. All rights reserved. Objective This study aimed to determine whether VNS applied during ischemia or at the onset of reperfusion exerts differential cardioprotection against cardiac I/R injury. Methods Twenty-eight swine (25-30 kg) were randomized into 4 groups: Control (...