Comparative outcome of Thai pediatric osteosarcoma treated with two protocols: The role of high-dose methotrexate (HDMTX) in a single institute experience

• Main Authors: Choeyprasert,W., Pakakasama,S., Sirachainan,N., Songdej,D., Chuansumrit,A., Anurathapan,U., Hongeng,S., Nartthanarung,A.
• Format: Article
• Published: Asian Pacific Organization for Cancer Prevention 2015
• Subjects: Cancer Research; Oncology; Epidemiology; Public Health, Environmental and Occupational Health
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84921496587&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38368
• Institution: Chiang Mai University

Background: High-dose methotrexate (HD-MTX) is recognized as an efficient component of therapy against pediatric osteosarcoma in combination with other drugs such as cisplatin (CDP), carboplatin (CBDCA), doxorubicin (ADM), etoposide (VP-16) and ifosfamide (IFO). Objectives: To demonstrate the feasib...