Cardiomyopathy associated with iron overload: How does iron enter myocytes and what are the implications for pharmacological therapy?

• Main Authors: Wijarnpreecha,K., Kumfu,S., Chattipakorn,S.C., Chattipakorn,N.
• Format: Review
• Published: Informa Healthcare 2015
• Subjects: Clinical Biochemistry; Hematology; Genetics (clinical); Biochemistry (medical)
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84921923611&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38372
• Institution: Chiang Mai University

© 2015 Informa Healthcare USA, Inc. Iron overload cardiomyopathy is one of the most common causes of death in thalassemia patients. Although new iron chelating agents have been developed, the mortality rate from heart failure remains elevated as a result of iron overload. This could be due to the fa...