SAffold viruses in pediatric patients with diarrhea in Thailand

• Main Authors: Yodmeeklin,A., Khamrin,P., Chuchaona,W., Saikruang,W., Malasao,R., Chaimongkol,N., Kongsricharoern,T., Ukarapol,N., Maneekarn,N.
• Format: Article
• Published: Wiley-Liss Inc. 2015
• Subjects: Infectious Diseases; Virology
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84922843444&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38390
• Institution: Chiang Mai University

© 2015 Wiley Periodicals, Inc. Saffold virus (SAFV) is a newly discovered human virus which is classified into the genus Cardiovirus of the family Picornaviridae. A total of 608 fecal specimens collected during January 2012 to December 2013 from children with diarrhea in Chiang Mai, Thailand were investigated for SAFV by RT-nested PCR and sequence analysis. Of these, nine out of 608 (1.5%) were positive for SAFVs and four genotypes were identified, SAFV1, SAFV2, SAFV3, and SAFV4. SAFV mono-infection was found in five cases (CMH-S038-12, CMH-S071-12, CMH-S102-12, CMH-N029-12, and CMH-S048-13), while co-infection with other viruses causing diarrhea was observed in four cases (CMH-S021-12, CMH-S115-12, CMH-N048-13 and CMH-N103-13). This study provides more information about the genetic background of SAFV circulating in pediatric patients with diarrhea in Thailand.