Divergent targets of Aspergillus fumigatus AcuK and AcuM transcription factors during growth in vitro versus invasive disease

• Main Authors: Pongpom,M., Liu,H., Xu,W., Snarr,B.D., Sheppard,D.C., Mitchell,A.P., Filler,S.G.
• Format: Article
• Published: American Society for Microbiology 2015
• Subjects: Parasitology; Microbiology; Immunology; Infectious Diseases
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84923012197&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38393
• Institution: Chiang Mai University

© 2015, American Society for Microbiology. In Aspergillus nidulans, the AcuK and AcuM transcription factors form a complex that regulates gluconeogenesis. In Aspergillus fumigatus, AcuM governs gluconeogenesis and iron acquisition in vitro and virulence in immunosuppressed mice. However, the functio...