Pretreatment HIV Drug Resistance and HIV-1 Subtype C Are Independently Associated with Virologic Failure: Results from the Multinational PEARLS (ACTG A5175) Clinical Trial

• Main Authors: Kantor R., Smeaton L., Vardhanabhuti S., Hudelson S., Wallis C., Tripathy S., Morgado M., Saravanan S., Balakrishnan P., Reitsma M., Hart S., Mellors J., Halvas E., Grinsztejn B., Hosseinipour M., Kumwenda J., La Rosa A., Lalloo U., Lama J., Rassool M., Santos B., Supparatpinyo K., Hakim J., Flanigan T., Kumarasamy N., Campbell T., Eshleman S.
• Format: Article
• Published: Oxford University Press 2015
• Subjects: Medicine (all); Infectious Diseases; Microbiology (medical)
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84929208014&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38484
• Institution: Chiang Mai University

© 2015 The Author. Background. Evaluation of pretreatment HIV genotyping is needed globally to guide treatment programs. We examined the association of pretreatment (baseline) drug resistance and subtype with virologic failure in a multinational, randomized clinical trial that evaluated 3 antiretrov...