Cardioprotective Effects of Metformin and Vildagliptin in Adult Rats with Insulin Resistance Induced by a High-Fat Diet

• Main Authors: Apaijai N., Pintana H., Chattipakorn S.C., Chattipakorn N.
• 格式: Article
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.ncbi.nlm.nih.gov/pubmed/22621958; http://www.scopus.com/inward/record.url?eid=2-s2.0-84864382843&partnerID=40&md5=23437b77a722ac87bd0c08750aebbfdd; http://cmuir.cmu.ac.th/handle/6653943832/3850
• 機構: Chiang Mai University

Insulin resistance has been shown to be associated with cardiac sympathovagal imbalance, myocardial dysfunction, and cardiac mitochondrial dysfunction. Whereas metformin is a widely used antidiabetic drug to improve insulin resistance, vildagliptin is a novel oral antidiabetic drug in a group of dip...