Biodegradable nanoparticles surface modification techniques with cIBR peptide targeting to LFA-1 expressing leukemic cells

• Main Authors: Phongpradist R., Chittasupho C., Intasai N., Siahaan T., Berkland C., Charoenkwan P., Anuchapreeda S., Ampasavate C.
• Format: Article
• Published: American Society of Mechanical Engineers(ASME) 2015
• Subjects: Electrical and Electronic Engineering; Medicine (all); Materials Science (all)
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84881137715&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38540
• Institution: Chiang Mai University

The lymphocyte function associated antigen-1 (LFA-1) is evaluated for a targeting carrier in leukemia. The cIBR peptide was utilized as the targeting moiety for the drug carrier in direct targeting to LFA-1 expressing cancer cells. This study aims to evaluate the effects of the cIBR peptide conjugat...