Enhancing phenolic contents and antioxidant potentials of antidesma thwaitesianum by supercritical carbon dioxide extraction

© 2015 Warut Poontawee et al. Supercritical fluid extraction (SFE) has increasingly gained attention as an alternative technique for extraction of natural products without leaving toxic residues in extracts. Antidesma thwaitesianum Muell. Arg. (Phyllanthaceae), or ma mao, has been reported to exhibi...

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Main Authors: Poontawee W., Natakankitkul S., Wongmekiat O.
Format: Article
Published: Hindawi Publishing Corporation 2015
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Online Access:http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84929376949&origin=inward
http://cmuir.cmu.ac.th/handle/6653943832/38566
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-385662015-06-16T07:50:30Z Enhancing phenolic contents and antioxidant potentials of antidesma thwaitesianum by supercritical carbon dioxide extraction Poontawee W. Natakankitkul S. Wongmekiat O. Analytical Chemistry Chemical Engineering (all) Computer Science Applications Instrumentation © 2015 Warut Poontawee et al. Supercritical fluid extraction (SFE) has increasingly gained attention as an alternative technique for extraction of natural products without leaving toxic residues in extracts. Antidesma thwaitesianum Muell. Arg. (Phyllanthaceae), or ma mao, has been reported to exhibit antioxidant health benefits due to its phenolic constituents. To determine whether SFE technique could impact on phenolic contents and associated antioxidant potentials, ripe fruits of Antidesma thwaitesianum (Phyllanthaceae) were extracted using supercritical carbon dioxide (SC-CO<inf>2</inf>) and conventional solvents (ethanol, water). The results showed that the SC-CO<inf>2</inf> extract contained significantly higher yield, total phenolic, flavonoid, and proanthocyanidin contents than those obtained from ethanol and water. It also demonstrated the greatest antioxidant activities as assessed by ABTS radical cation decolorization, DPPH radical scavenging, and ferric reducing antioxidant power (FRAP) assays. Further analysis using high-performance liquid chromatography with diode array and mass spectrometry detectors (HPLC-DAD/MSD) revealed the presence of catechin as a major phenolic compound of Antidesma thwaitesianum (Phyllanthaceae), with the maximum amount detected in the SC-CO<inf>2</inf> extract. These data indicate that SFE technology improves both quantity and quality of Antidesma thwaitesianum fruit extract. The findings added more reliability of using this technique to produce high added value products from this medicinal plant. 2015-06-16T07:50:30Z 2015-06-16T07:50:30Z 2015-01-01 Article 20908865 2-s2.0-84929376949 10.1155/2015/956298 http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84929376949&origin=inward http://cmuir.cmu.ac.th/handle/6653943832/38566 Hindawi Publishing Corporation
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Analytical Chemistry
Chemical Engineering (all)
Computer Science Applications
Instrumentation
spellingShingle Analytical Chemistry
Chemical Engineering (all)
Computer Science Applications
Instrumentation
Poontawee W.
Natakankitkul S.
Wongmekiat O.
Enhancing phenolic contents and antioxidant potentials of antidesma thwaitesianum by supercritical carbon dioxide extraction
description © 2015 Warut Poontawee et al. Supercritical fluid extraction (SFE) has increasingly gained attention as an alternative technique for extraction of natural products without leaving toxic residues in extracts. Antidesma thwaitesianum Muell. Arg. (Phyllanthaceae), or ma mao, has been reported to exhibit antioxidant health benefits due to its phenolic constituents. To determine whether SFE technique could impact on phenolic contents and associated antioxidant potentials, ripe fruits of Antidesma thwaitesianum (Phyllanthaceae) were extracted using supercritical carbon dioxide (SC-CO<inf>2</inf>) and conventional solvents (ethanol, water). The results showed that the SC-CO<inf>2</inf> extract contained significantly higher yield, total phenolic, flavonoid, and proanthocyanidin contents than those obtained from ethanol and water. It also demonstrated the greatest antioxidant activities as assessed by ABTS radical cation decolorization, DPPH radical scavenging, and ferric reducing antioxidant power (FRAP) assays. Further analysis using high-performance liquid chromatography with diode array and mass spectrometry detectors (HPLC-DAD/MSD) revealed the presence of catechin as a major phenolic compound of Antidesma thwaitesianum (Phyllanthaceae), with the maximum amount detected in the SC-CO<inf>2</inf> extract. These data indicate that SFE technology improves both quantity and quality of Antidesma thwaitesianum fruit extract. The findings added more reliability of using this technique to produce high added value products from this medicinal plant.
format Article
author Poontawee W.
Natakankitkul S.
Wongmekiat O.
author_facet Poontawee W.
Natakankitkul S.
Wongmekiat O.
author_sort Poontawee W.
title Enhancing phenolic contents and antioxidant potentials of antidesma thwaitesianum by supercritical carbon dioxide extraction
title_short Enhancing phenolic contents and antioxidant potentials of antidesma thwaitesianum by supercritical carbon dioxide extraction
title_full Enhancing phenolic contents and antioxidant potentials of antidesma thwaitesianum by supercritical carbon dioxide extraction
title_fullStr Enhancing phenolic contents and antioxidant potentials of antidesma thwaitesianum by supercritical carbon dioxide extraction
title_full_unstemmed Enhancing phenolic contents and antioxidant potentials of antidesma thwaitesianum by supercritical carbon dioxide extraction
title_sort enhancing phenolic contents and antioxidant potentials of antidesma thwaitesianum by supercritical carbon dioxide extraction
publisher Hindawi Publishing Corporation
publishDate 2015
url http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84929376949&origin=inward
http://cmuir.cmu.ac.th/handle/6653943832/38566
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