A mechanism of ineffective erythropoiesis in β-thalassemia/Hb E disease

• المؤلفون الرئيسيون: Lithanatudom,P., Leecharoenkiat,A., Wannatung,T., Svasti,S.L., Fucharoen,S., Smith,D.R.
• التنسيق: مقال
• منشور في: Ferrata Storti Foundation 2015
• الموضوعات: Hematology
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77952393677&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38580

Background Cells respond to stress stimuli through a number of response pathways, of which one of the most important and well characterized is the unfolded protein response. Despite a large body of work which suggests that stress in erythroblasts may play a pivotal role in the pathogenesis of β-thal...