Increased erythropoiesis of β-thalassaemia/Hb E proerythroblasts is mediated by high basal levels of ERK1/2 activation

β-thalassaemia is one of the most common inherited anaemias, arising from a partial or complete loss of β-globin chain synthesis. In severe cases, marked bone marrow erythroid hyperplasia, believed to result from erythropoietin (EPO)-mediated feedback from the anaemic condition is common, however, a...

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Bibliographic Details
Main Authors: Tirawat Wannatung, Pathrapol Lithanatudom, Amporn Leecharoenkiat, Saovaros Svasti, Suthat Fucharoen, Duncan R. Smith
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/27938
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Institution: Mahidol University