More realistic model for simulating min protein dynamics: Lattice boltzmann method incorporating the role of nucleoids
The dynamics of Min proteins plays a center role in accurate cell division. Although the nucleoids may presumably play an important role in prokaryotic cell division, there is a lack of models to account for its participation. In this work, we apply the lattice Boltzmann method to investigate protei...
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World Academy of Science Engineering and Technology
2015
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th-cmuir.6653943832-385872015-06-16T07:53:27Z More realistic model for simulating min protein dynamics: Lattice boltzmann method incorporating the role of nucleoids Yojina,J. Ngamsaad,W. Nuttavut,N. Triampo,D. Lenbury,Y.W. Triampo,W. Kanthang,P. Sriyab,S. Mathematics (all) Computer Science (all) The dynamics of Min proteins plays a center role in accurate cell division. Although the nucleoids may presumably play an important role in prokaryotic cell division, there is a lack of models to account for its participation. In this work, we apply the lattice Boltzmann method to investigate protein oscillation based on a mesoscopic model that takes into account the nucleoid's role. We found that our numerical results are in reasonably good agreement with the previous experimental results On comparing with the other computational models without the presence of nucleoids, the highlight of our finding is that the local densities of MinD and MinE on the cytoplasmic membrane increases, especially along the cell width, when the size of the obstacle increases, leading to a more distinct cap-like structure at the poles. This feature indicated the realistic pattern and reflected the combination of Min protein dynamics and nucleoid's role. 2015-06-16T07:53:27Z 2015-06-16T07:53:27Z 2010-11-17 Article 20103905 2-s2.0-78149437922 http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=78149437922&origin=inward http://cmuir.cmu.ac.th/handle/6653943832/38587 World Academy of Science Engineering and Technology |
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Mathematics (all) Computer Science (all) Yojina,J. Ngamsaad,W. Nuttavut,N. Triampo,D. Lenbury,Y.W. Triampo,W. Kanthang,P. Sriyab,S. More realistic model for simulating min protein dynamics: Lattice boltzmann method incorporating the role of nucleoids |
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The dynamics of Min proteins plays a center role in accurate cell division. Although the nucleoids may presumably play an important role in prokaryotic cell division, there is a lack of models to account for its participation. In this work, we apply the lattice Boltzmann method to investigate protein oscillation based on a mesoscopic model that takes into account the nucleoid's role. We found that our numerical results are in reasonably good agreement with the previous experimental results On comparing with the other computational models without the presence of nucleoids, the highlight of our finding is that the local densities of MinD and MinE on the cytoplasmic membrane increases, especially along the cell width, when the size of the obstacle increases, leading to a more distinct cap-like structure at the poles. This feature indicated the realistic pattern and reflected the combination of Min protein dynamics and nucleoid's role. |
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Article |
author |
Yojina,J. Ngamsaad,W. Nuttavut,N. Triampo,D. Lenbury,Y.W. Triampo,W. Kanthang,P. Sriyab,S. |
author_facet |
Yojina,J. Ngamsaad,W. Nuttavut,N. Triampo,D. Lenbury,Y.W. Triampo,W. Kanthang,P. Sriyab,S. |
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Yojina,J. |
title |
More realistic model for simulating min protein dynamics: Lattice boltzmann method incorporating the role of nucleoids |
title_short |
More realistic model for simulating min protein dynamics: Lattice boltzmann method incorporating the role of nucleoids |
title_full |
More realistic model for simulating min protein dynamics: Lattice boltzmann method incorporating the role of nucleoids |
title_fullStr |
More realistic model for simulating min protein dynamics: Lattice boltzmann method incorporating the role of nucleoids |
title_full_unstemmed |
More realistic model for simulating min protein dynamics: Lattice boltzmann method incorporating the role of nucleoids |
title_sort |
more realistic model for simulating min protein dynamics: lattice boltzmann method incorporating the role of nucleoids |
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World Academy of Science Engineering and Technology |
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2015 |
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http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=78149437922&origin=inward http://cmuir.cmu.ac.th/handle/6653943832/38587 |
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