Modiolide and pyrone derivatives from the sea fan-derived fungus Curvularia sp. PSU-F22

Modiolide and pyrone derivatives from the sea fan-derived fungus Curvularia sp. PSU-F22

Investigation of secondary metabolites from the sea fan-derived fungus Curvularia sp. PSU-F22 resulted in isolation of three new metabolites, curvulapyrone (1), curvulalide (2) and curvulalic acid (3) together with six known compounds, modiolides A (4) and B (5), pyrenolide A (6), stagonolide E (7),...

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Bibliographic Details
Main Authors: Trisuwan,K., Rukachaisirikul,V., Phongpaichit,S., Preedanon,S., Sakayaroj,J.
Format: Article
Published: Pharmaceutical Society of Korea 2015
Subjects:
Drug Discovery
Molecular Medicine
Organic Chemistry
Online Access:http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79960276297&origin=inward
http://cmuir.cmu.ac.th/handle/6653943832/38598
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Institution: Chiang Mai University
Description
Summary:Investigation of secondary metabolites from the sea fan-derived fungus Curvularia sp. PSU-F22 resulted in isolation of three new metabolites, curvulapyrone (1), curvulalide (2) and curvulalic acid (3) together with six known compounds, modiolides A (4) and B (5), pyrenolide A (6), stagonolide E (7), mycoepoxydiene (8), and deacetylmycoepoxydiene (9). Their antimicrobial activity against Staphylococcus aureus ATCC 25923, methicillin-resistant S. aureus and Microsporum gypseum SH-MU-4 were examined. © 2011 The Pharmaceutical Society of Korea and Springer Netherlands.

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