Limit of sensitivity for melting curve screening for α-thalassemia

• Main Authors: Sriiam,S., Leecharoenkiat,A., Lithanatudom,P., Munkongdee,T., Svasti,S.L., Smith,D.R.
• Format: Article
• Published: IOS Press 2015
• Subjects: Medicine (all); Biochemistry, Genetics and Molecular Biology (all)
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84871668495&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38658
• Institution: Chiang Mai University

Background: Thalassemia is a major inherited disease in Thailand, with a large number of people being either directly affected or carrying the trait. The Southeast Asian α-thalassemia 1 deletion (--SEA) is the most common α-thalassemia 1 type, with a high number of carriers in Thai population. Indiv...