New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities

New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities

Seven new neolignans and a new lignan were isolated from the leaves and the stems of Miliusa fragrans, along with nine known polyphenolic compounds. Their structures were established through analysis of spectroscopic data, including 1H and 13C NMR, COSY, NOESY, HSQC, HMBC, and HRMS. The isolates wer...

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Main Authors: Sawasdee,K., Chaowasku,T., Lipipun,V., Dufat,T.H., Michel,S., Likhitwitayawuid,K.
Format: Article
Published: Elsevier Limited 2015
Subjects:
Drug Discovery
Organic Chemistry
Biochemistry
Online Access:http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84879843072&origin=inward
http://cmuir.cmu.ac.th/handle/6653943832/38695
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-386952015-06-16T07:53:58Z New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities Sawasdee,K. Chaowasku,T. Lipipun,V. Dufat,T.H. Michel,S. Likhitwitayawuid,K. Drug Discovery Organic Chemistry Biochemistry Seven new neolignans and a new lignan were isolated from the leaves and the stems of Miliusa fragrans, along with nine known polyphenolic compounds. Their structures were established through analysis of spectroscopic data, including 1H and 13C NMR, COSY, NOESY, HSQC, HMBC, and HRMS. The isolates were also evaluated for their inhibitory activity against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) and their cytotoxicity against KB, MCF7, and NCI-H187 cancer cells. © 2013 Elsevier Ltd. All rights reserved. 2015-06-16T07:53:58Z 2015-06-16T07:53:58Z 2013-08-07 Article 00404039 2-s2.0-84879843072 10.1016/j.tetlet.2013.05.144 http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84879843072&origin=inward http://cmuir.cmu.ac.th/handle/6653943832/38695 Elsevier Limited
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Drug Discovery
Organic Chemistry
Biochemistry
spellingShingle Drug Discovery
Organic Chemistry
Biochemistry
Sawasdee,K.
Chaowasku,T.
Lipipun,V.
Dufat,T.H.
Michel,S.
Likhitwitayawuid,K.
New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities
description Seven new neolignans and a new lignan were isolated from the leaves and the stems of Miliusa fragrans, along with nine known polyphenolic compounds. Their structures were established through analysis of spectroscopic data, including 1H and 13C NMR, COSY, NOESY, HSQC, HMBC, and HRMS. The isolates were also evaluated for their inhibitory activity against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) and their cytotoxicity against KB, MCF7, and NCI-H187 cancer cells. © 2013 Elsevier Ltd. All rights reserved.
format Article
author Sawasdee,K.
Chaowasku,T.
Lipipun,V.
Dufat,T.H.
Michel,S.
Likhitwitayawuid,K.
author_facet Sawasdee,K.
Chaowasku,T.
Lipipun,V.
Dufat,T.H.
Michel,S.
Likhitwitayawuid,K.
author_sort Sawasdee,K.
title New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities
title_short New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities
title_full New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities
title_fullStr New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities
title_full_unstemmed New neolignans and a lignan from Miliusa fragrans, and their anti-herpetic and cytotoxic activities
title_sort new neolignans and a lignan from miliusa fragrans, and their anti-herpetic and cytotoxic activities
publisher Elsevier Limited
publishDate 2015
url http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84879843072&origin=inward
http://cmuir.cmu.ac.th/handle/6653943832/38695
_version_ 1681421520208920576

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