QM-MM investigation on chorismate synthase enzyme role

• Main Author: Lawan,N.
• Format: Article
• Published: Chiang Mai University 2015
• Subjects: Physics and Astronomy (all); Chemistry (all); Materials Science (all); Mathematics (all); Biochemistry, Genetics and Molecular Biology (all)
• Online Access: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84905722622&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38753
• Institution: Chiang Mai University

Chorismate is a key intermediate in the biosynthesis of many aromatic compounds, including the aromatic amino acids. Chorismate synthase (CS) is an enzyme responsible for the biosynthesis of chorismate. Although several proposals have been made, the role of this enzyme is still unclear. In this work...