Characterization and expression of cathepsin B2 in Fasciola gigantica

• Main Authors: Chantree P., Wanichanon C., Phatsara M., Meemon K., Sobhon P.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84866395887&partnerID=40&md5=277e1d67bb45bf9fc59466755e7540a8; http://cmuir.cmu.ac.th/handle/6653943832/3878
• Institution: Chiang Mai University

Fasciola gigantica cathepsin B belongs to a family of cysteine proteases which is involved in invasion of host tissues. In this study, the recombinant cathepsin B2 (rFgCatB2), synthesized in Pichia pastoris, showed enzymatic activity on a fluorometric substrate Z-Phe-Arg-AMC and gelatin. Furthermore...