A highly discriminatory multilocus microsatellite typing (MLMT) system for Penicillium marneffei

A highly discriminatory multilocus microsatellite typing (MLMT) system for Penicillium marneffei

For eukaryotic pathogens that are depauperate in genetic variation, multilocus microsatellite typing (MLMT) offers an accurate and reproducible method of characterizing genetic diversity; herein we describe the development of an MLMT system for the emerging pathogenic fungus Penicillium marneffei ba...

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Main Authors: Fisher M.C., De Hoog S., Vanittanakom N.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-4344691284&partnerID=40&md5=eb8a00cfdc68148495dec25cb3887a6e
http://cmuir.cmu.ac.th/handle/6653943832/3911
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-39112014-08-30T02:35:28Z A highly discriminatory multilocus microsatellite typing (MLMT) system for Penicillium marneffei Fisher M.C. De Hoog S. Vanittanakom N. For eukaryotic pathogens that are depauperate in genetic variation, multilocus microsatellite typing (MLMT) offers an accurate and reproducible method of characterizing genetic diversity; herein we describe the development of an MLMT system for the emerging pathogenic fungus Penicillium marneffei based on 23 microsatellite loci. Screening isolates held within the Centraalbureau voor Schimmelcultures culture collection demonstrate high levels of genetic diversity and 100% reproducibility. This MLMT system provides a powerful epidemiological tool to analyse the underlying parameters that are responsible for the emergence of P. marneffei in human HIV-positive populations. 2014-08-30T02:35:28Z 2014-08-30T02:35:28Z 2004 Article 14718278 10.1111/j.1471-8286.2004.00710.x MENOC http://www.scopus.com/inward/record.url?eid=2-s2.0-4344691284&partnerID=40&md5=eb8a00cfdc68148495dec25cb3887a6e http://cmuir.cmu.ac.th/handle/6653943832/3911 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description For eukaryotic pathogens that are depauperate in genetic variation, multilocus microsatellite typing (MLMT) offers an accurate and reproducible method of characterizing genetic diversity; herein we describe the development of an MLMT system for the emerging pathogenic fungus Penicillium marneffei based on 23 microsatellite loci. Screening isolates held within the Centraalbureau voor Schimmelcultures culture collection demonstrate high levels of genetic diversity and 100% reproducibility. This MLMT system provides a powerful epidemiological tool to analyse the underlying parameters that are responsible for the emergence of P. marneffei in human HIV-positive populations.
format Article
author Fisher M.C.
De Hoog S.
Vanittanakom N.
spellingShingle Fisher M.C.
De Hoog S.
Vanittanakom N.
A highly discriminatory multilocus microsatellite typing (MLMT) system for Penicillium marneffei
author_facet Fisher M.C.
De Hoog S.
Vanittanakom N.
author_sort Fisher M.C.
title A highly discriminatory multilocus microsatellite typing (MLMT) system for Penicillium marneffei
title_short A highly discriminatory multilocus microsatellite typing (MLMT) system for Penicillium marneffei
title_full A highly discriminatory multilocus microsatellite typing (MLMT) system for Penicillium marneffei
title_fullStr A highly discriminatory multilocus microsatellite typing (MLMT) system for Penicillium marneffei
title_full_unstemmed A highly discriminatory multilocus microsatellite typing (MLMT) system for Penicillium marneffei
title_sort highly discriminatory multilocus microsatellite typing (mlmt) system for penicillium marneffei
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-4344691284&partnerID=40&md5=eb8a00cfdc68148495dec25cb3887a6e
http://cmuir.cmu.ac.th/handle/6653943832/3911
_version_ 1681420137936191488

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