Meta-regression of risk factors for microalbuminuria in type 2 diabetes

We aimed to determine the risk factors associated with microalbuminuria in type 2 diabetes patients through a systematic review and meta-regression analysis. The analyzed studies were obtained from PubMed, Scopus, British Medical Journal and ProQuest databases. All studies published from 2000 to 200...

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Main Authors: Mongkolsomlit S., Patumanond J., Tawichasri C., Komoltri C., Rawdaree P.
Format: Review
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84862564542&partnerID=40&md5=fa21bc83ba0d544b66cda25f4792cac1
http://cmuir.cmu.ac.th/handle/6653943832/3923
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-39232014-08-30T02:35:28Z Meta-regression of risk factors for microalbuminuria in type 2 diabetes Mongkolsomlit S. Patumanond J. Tawichasri C. Komoltri C. Rawdaree P. We aimed to determine the risk factors associated with microalbuminuria in type 2 diabetes patients through a systematic review and meta-regression analysis. The analyzed studies were obtained from PubMed, Scopus, British Medical Journal and ProQuest databases. All studies published from 2000 to 2009 were included. The search yielded 1,243 citations, of which 22 studies were analyzed. Pooled odds ratio estimates were obtained using a random effect model. The association of each risk factor with microalbuminuria was examined after adjusting for age and sex using meta-regression analysis. The adjusted odds ratio was 1.26 (95% CI 1.08-1.46) for systolic blood pressure; 1.16 (95% CI 1.03-1.31) for diastolic blood pressure; 1.43 (95% CI 1.14-1.80) for fasting plasma glucose level; 1.37 (95% CI 0.95-1.98) for smoking and 1.49 (95% CI 0.91-2.46) for waist circumference. The risk factors associated with microalbuminuria were found to be poor glycemic control, uncontrolled hypertension, smoking and central obesity. There is an urgent need to launch a health promotion program for changes in individual health behaviors to mitigate these risk factors for microalbuminuria in patients with type 2 diabetes. 2014-08-30T02:35:28Z 2014-08-30T02:35:28Z 2012 Review 1251562 http://www.scopus.com/inward/record.url?eid=2-s2.0-84862564542&partnerID=40&md5=fa21bc83ba0d544b66cda25f4792cac1 http://cmuir.cmu.ac.th/handle/6653943832/3923 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description We aimed to determine the risk factors associated with microalbuminuria in type 2 diabetes patients through a systematic review and meta-regression analysis. The analyzed studies were obtained from PubMed, Scopus, British Medical Journal and ProQuest databases. All studies published from 2000 to 2009 were included. The search yielded 1,243 citations, of which 22 studies were analyzed. Pooled odds ratio estimates were obtained using a random effect model. The association of each risk factor with microalbuminuria was examined after adjusting for age and sex using meta-regression analysis. The adjusted odds ratio was 1.26 (95% CI 1.08-1.46) for systolic blood pressure; 1.16 (95% CI 1.03-1.31) for diastolic blood pressure; 1.43 (95% CI 1.14-1.80) for fasting plasma glucose level; 1.37 (95% CI 0.95-1.98) for smoking and 1.49 (95% CI 0.91-2.46) for waist circumference. The risk factors associated with microalbuminuria were found to be poor glycemic control, uncontrolled hypertension, smoking and central obesity. There is an urgent need to launch a health promotion program for changes in individual health behaviors to mitigate these risk factors for microalbuminuria in patients with type 2 diabetes.
format Review
author Mongkolsomlit S.
Patumanond J.
Tawichasri C.
Komoltri C.
Rawdaree P.
spellingShingle Mongkolsomlit S.
Patumanond J.
Tawichasri C.
Komoltri C.
Rawdaree P.
Meta-regression of risk factors for microalbuminuria in type 2 diabetes
author_facet Mongkolsomlit S.
Patumanond J.
Tawichasri C.
Komoltri C.
Rawdaree P.
author_sort Mongkolsomlit S.
title Meta-regression of risk factors for microalbuminuria in type 2 diabetes
title_short Meta-regression of risk factors for microalbuminuria in type 2 diabetes
title_full Meta-regression of risk factors for microalbuminuria in type 2 diabetes
title_fullStr Meta-regression of risk factors for microalbuminuria in type 2 diabetes
title_full_unstemmed Meta-regression of risk factors for microalbuminuria in type 2 diabetes
title_sort meta-regression of risk factors for microalbuminuria in type 2 diabetes
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-84862564542&partnerID=40&md5=fa21bc83ba0d544b66cda25f4792cac1
http://cmuir.cmu.ac.th/handle/6653943832/3923
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