Potent Melanin Production Enhancement of Human Tyrosinase Gene by Tat and an Entrapment in Elastic Cationic Niosomes: Potential Application in Vitiligo Gene Therapy

• Main Authors: Manosroi J., Khositsuntiwong N., Gotz F., Werner R.G., Manosroi W., Manosroi A.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84868106277&partnerID=40&md5=10d546917cc9ec68c7117dd852581de1; http://cmuir.cmu.ac.th/handle/6653943832/3944
• Institution: Chiang Mai University

Potent melanin production enhancement of human tyrosinase plasmid (pAH7/Tyr, P) in mouse melanoma cells (B 16F 10) by Tat peptide (T) and an entrapment in elastic cationic niosomes (E) was described. The E composed of Tween 61/cholesterol/dodecyl dimethyl ammonium bromide at 1:1:0.5 molar ratio was...