Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones

© 2017 American Chemical Society. 5-Substituted-2-ethoxy-1,3,4-oxadiazoles were conveniently prepared through a one-pot sequential N-acylation/dehydrative cyclization between ethyl carbazate and N-acylbenzotriazoles in the presence of Ph 3 P-I 2 as a dehydrating agent. Subsequent treatment with a s...

Full description

Saved in:

Bibliographic Details
Main Authors:	Wet-Osot S., Phakhodee W., Pattarawarapan M.
Format:	Journal
Published:	2017
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85029484222&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/40105
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Chiang Mai University

id	th-cmuir.6653943832-40105
record_format	dspace
spelling	th-cmuir.6653943832-401052017-09-28T04:05:18Z Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones Wet-Osot S. Phakhodee W. Pattarawarapan M. © 2017 American Chemical Society. 5-Substituted-2-ethoxy-1,3,4-oxadiazoles were conveniently prepared through a one-pot sequential N-acylation/dehydrative cyclization between ethyl carbazate and N-acylbenzotriazoles in the presence of Ph 3 P-I 2 as a dehydrating agent. Subsequent treatment with a stoichiometric amount of alkyl halides (X = Cl, Br, I) enables a rapid access to a variety of 3,5-disubstituted 1,3,4-oxadiazol-2(3H)-ones in good to excellent yields. 2017-09-28T04:05:18Z 2017-09-28T04:05:18Z 18 Journal 00223263 2-s2.0-85029484222 10.1021/acs.joc.7b01863 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85029484222&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/40105
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
description	© 2017 American Chemical Society. 5-Substituted-2-ethoxy-1,3,4-oxadiazoles were conveniently prepared through a one-pot sequential N-acylation/dehydrative cyclization between ethyl carbazate and N-acylbenzotriazoles in the presence of Ph 3 P-I 2 as a dehydrating agent. Subsequent treatment with a stoichiometric amount of alkyl halides (X = Cl, Br, I) enables a rapid access to a variety of 3,5-disubstituted 1,3,4-oxadiazol-2(3H)-ones in good to excellent yields.
format	Journal
author	Wet-Osot S. Phakhodee W. Pattarawarapan M.
spellingShingle	Wet-Osot S. Phakhodee W. Pattarawarapan M. Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones
author_facet	Wet-Osot S. Phakhodee W. Pattarawarapan M.
author_sort	Wet-Osot S.
title	Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones
title_short	Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones
title_full	Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones
title_fullStr	Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones
title_full_unstemmed	Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones
title_sort	application of n-acylbenzotriazoles in the synthesis of 5-substituted 2-ethoxy-1,3,4-oxadiazoles as building blocks toward 3,5-disubstituted 1,3,4-oxadiazol-2(3h)-ones
publishDate	2017
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85029484222&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/40105
_version_	1681421748500692992

Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones

Similar Items