Massive parallel sequencing as a new diagnostic approach for phenylketonuria and tetrahydrobiopterin-deficiency in Thailand

• Main Authors: Chaiyasap P., Ittiwut C., Srichomthong C., Sangsin A., Suphapeetiporn K., Shotelersuk V.
• 格式: 雜誌
• 出版: 2017
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85029433997&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/40107

© 2017 The Author(s). Background: Hyperphenylalaninemia (HPA) can be classified into phenylketonuria (PKU) which is caused by mutations in the phenylalanine hydroxylase (PAH) gene, and BH4 deficiency caused by alterations in genes involved in tetrahydrobiopterin (BH4) biosynthesis pathway. Dietary r...