Kuguacin J isolated from bitter melon leaves modulates paclitaxel sensitivity in drug-resistant human ovarian cancer cells

• Main Authors: Pitchakarn P., Umsumarng S., Mapoung S., Ting P., Temviriyanukul P., Punfa W., Pompimon W., Limtrakul P.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85021070299&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/40351
• Institution: Chiang Mai University

© 2017 The Japanese Society of Pharmacognosy and Springer Japan KK We previously reported the multidrug resistance-reversing ability of kuguacin J (KJ) in cervical cancer cells via the inhibition of P-glycoprotein (P-gp) function. This study investigated whether KJ could promote cisplatin- and pacli...