Semisynthesis and biological evaluation of prenylated resveratrol derivatives as multi-targeted agents for Alzheimer’s disease

• Main Authors: Puksasook T., Kimura S., Tadtong S., Jiaranaikulwanitch J., Pratuangdejkul J., Kitphati W., Suwanborirux K., Saito N., Nukoolkarn V.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85020739007&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/40367
• Institution: Chiang Mai University

© 2017 The Japanese Society of Pharmacognosy and Springer Japan Abstract: A series of prenylated resveratrol derivatives were designed, semisynthesized and biologically evaluated for inhibition of β-secretase (BACE1) and amyloid-β (Aβ) aggregation as well as free radical scavenging and neuroprotecti...