Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents
Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. We determined hepatitis B virus (HBV) suppression rates among 18 lamivudine (3TC)-experienced HBV-human immunodeficiency virus-coinfected adolescents after treatment with tenofovir disoproxil fumurate (TDF). At TDF initiation, their m...
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th-cmuir.6653943832-406232017-09-28T04:10:34Z Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents Aurpibul L. Lumbiganon P. Hansudewechakul R. Kanjanavanit S. Bunupuradah T. Kosalaraksa P. Taeprasert P. Puthanakit T. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. We determined hepatitis B virus (HBV) suppression rates among 18 lamivudine (3TC)-experienced HBV-human immunodeficiency virus-coinfected adolescents after treatment with tenofovir disoproxil fumurate (TDF). At TDF initiation, their median age was 17.6 years, and duration of 3TC exposure was 7.3 years. Eleven patients (61%) achieved HBV DNA < 60 IU/mL after 48 weeks on TDF and 3TC which was similar to adult studies, although hepatitis B surface antigen loss or hepatitis B envelope antigen seroconversion did not occur. 2017-09-28T04:10:34Z 2017-09-28T04:10:34Z 4 Journal 08913668 2-s2.0-85007247655 10.1097/INF.0000000000001491 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85007247655&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/40623 |
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Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. We determined hepatitis B virus (HBV) suppression rates among 18 lamivudine (3TC)-experienced HBV-human immunodeficiency virus-coinfected adolescents after treatment with tenofovir disoproxil fumurate (TDF). At TDF initiation, their median age was 17.6 years, and duration of 3TC exposure was 7.3 years. Eleven patients (61%) achieved HBV DNA < 60 IU/mL after 48 weeks on TDF and 3TC which was similar to adult studies, although hepatitis B surface antigen loss or hepatitis B envelope antigen seroconversion did not occur. |
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Journal |
author |
Aurpibul L. Lumbiganon P. Hansudewechakul R. Kanjanavanit S. Bunupuradah T. Kosalaraksa P. Taeprasert P. Puthanakit T. |
spellingShingle |
Aurpibul L. Lumbiganon P. Hansudewechakul R. Kanjanavanit S. Bunupuradah T. Kosalaraksa P. Taeprasert P. Puthanakit T. Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents |
author_facet |
Aurpibul L. Lumbiganon P. Hansudewechakul R. Kanjanavanit S. Bunupuradah T. Kosalaraksa P. Taeprasert P. Puthanakit T. |
author_sort |
Aurpibul L. |
title |
Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents |
title_short |
Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents |
title_full |
Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents |
title_fullStr |
Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents |
title_full_unstemmed |
Response to Tenofovir Among Lamivudine-experienced Hepatitis B and HIV-coinfected Adolescents |
title_sort |
response to tenofovir among lamivudine-experienced hepatitis b and hiv-coinfected adolescents |
publishDate |
2017 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85007247655&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/40623 |
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1681421851671134208 |