Effects of L-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans

© 2016, Sports Medicine Research Center. Background: The effectiveness of L-carnitine supplementation has been met with conflicting findings when used by sedentary and athletic adults. Objectives: This study aimed to investigate the acute effects of L-carnitine supplementation on aerobic metabolic e...

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Main Authors: Leelarungrayub J., Pinkaew D., Klaphajone J., Eungpinichpong W., Bloomer R.
Format: Journal
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85017662067&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/40697
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-406972017-09-28T04:11:01Z Effects of L-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans Leelarungrayub J. Pinkaew D. Klaphajone J. Eungpinichpong W. Bloomer R. © 2016, Sports Medicine Research Center. Background: The effectiveness of L-carnitine supplementation has been met with conflicting findings when used by sedentary and athletic adults. Objectives: This study aimed to investigate the acute effects of L-carnitine supplementation on aerobic metabolic efficiency and lipid profiles in sedentary and athletic men. Methods: Fifteen sedentary (20.4 ± 1.5 years) and 15 athletic (21.5 ± 2.4 years) men were studied in durations of control, placebo intake and 2 g of L-carnitine supplementation. Lipid profiles, including triglyceride, cholesterol, high-density lipoprotein (HDL) and very-low density lipoprotein (VLDL), were determined before and 40 min after either the placebo or L-carnitine intake. Oxygen consumption (direct VO 2 ), ventilatory threshold (VT), and running time (RT) were recorded after a submaximal treadmill exercise test. Results: Direct VO 2 increased significantly at 80% of maximal heart rate after L-carnitine supplementation in both athletic and sedentary men, whereas, a statistical increase in VT and RT occurred only after L-carnitine use in athletes, when compared to the control and placebo subjects. The sedentary group showed no changes in lipid parameters, but triglyceride levels reduced significantly in the athletes after consuming L-carnitine. Conclusions: Acute L-carnitine supplementation possibly affects exercise performance and triglycerides in athletes rather than sedentary men. 2017-09-28T04:11:01Z 2017-09-28T04:11:01Z 1 Journal 2008000X 2-s2.0-85017662067 10.5812/asjsm.38707 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85017662067&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/40697
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description © 2016, Sports Medicine Research Center. Background: The effectiveness of L-carnitine supplementation has been met with conflicting findings when used by sedentary and athletic adults. Objectives: This study aimed to investigate the acute effects of L-carnitine supplementation on aerobic metabolic efficiency and lipid profiles in sedentary and athletic men. Methods: Fifteen sedentary (20.4 ± 1.5 years) and 15 athletic (21.5 ± 2.4 years) men were studied in durations of control, placebo intake and 2 g of L-carnitine supplementation. Lipid profiles, including triglyceride, cholesterol, high-density lipoprotein (HDL) and very-low density lipoprotein (VLDL), were determined before and 40 min after either the placebo or L-carnitine intake. Oxygen consumption (direct VO 2 ), ventilatory threshold (VT), and running time (RT) were recorded after a submaximal treadmill exercise test. Results: Direct VO 2 increased significantly at 80% of maximal heart rate after L-carnitine supplementation in both athletic and sedentary men, whereas, a statistical increase in VT and RT occurred only after L-carnitine use in athletes, when compared to the control and placebo subjects. The sedentary group showed no changes in lipid parameters, but triglyceride levels reduced significantly in the athletes after consuming L-carnitine. Conclusions: Acute L-carnitine supplementation possibly affects exercise performance and triglycerides in athletes rather than sedentary men.
format Journal
author Leelarungrayub J.
Pinkaew D.
Klaphajone J.
Eungpinichpong W.
Bloomer R.
spellingShingle Leelarungrayub J.
Pinkaew D.
Klaphajone J.
Eungpinichpong W.
Bloomer R.
Effects of L-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans
author_facet Leelarungrayub J.
Pinkaew D.
Klaphajone J.
Eungpinichpong W.
Bloomer R.
author_sort Leelarungrayub J.
title Effects of L-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans
title_short Effects of L-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans
title_full Effects of L-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans
title_fullStr Effects of L-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans
title_full_unstemmed Effects of L-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans
title_sort effects of l-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans
publishDate 2017
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85017662067&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/40697
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