Vaccine potential of recombinant cathepsin B against Fasciola gigantica

• Main Authors: Chantree P., Phatsara M., Meemon K., Chaichanasak P., Changklungmoa N., Kueakhai P., Lorsuwannarat N., Sangpairoj K., Songkoomkrong S., Wanichanon C., Itagaki T., Sobhon P.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84880422630&partnerID=40&md5=98815e53f77852f2d404bdf2791a980d; http://cmuir.cmu.ac.th/handle/6653943832/4136
• Institution: Chiang Mai University

In Fasciola gigantica, cathepsin Bs, especially cathepsin B2 and B3 are expressed in early juvenile stages, and are proposed to mediate the invasion of host tissues. Thus they are thought to be the target vaccine candidates that can block the invasion and migration of the juvenile parasite. To evalu...