Glucocorticoid receptor gene expression and promoter CpG modifications throughout the human brain

• Main Authors: Cao-Lei L., Suwansirikul S., Jutavijittum P., Meriaux S.B., Turner J.D., Muller C.P.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84884416988&partnerID=40&md5=4f30d20df1e10c04190f4a86a6873f16; http://www.ncbi.nlm.nih.gov/pubmed/23948638; http://cmuir.cmu.ac.th/handle/6653943832/4145
• Institution: Chiang Mai University

Glucocorticoids and the glucocorticoid (GR) and mineralocorticoid (MR) receptors have been implicated in many processes, particularly in negative feedback regulation of the hypothalamic-pituitary-adrenal axis. Epigenetically programmed GR alternative promoter usage underlies transcriptional control...