Incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: The multicenter thai university-based surgical intensive care unit (THAI-SICU) study

© 2016, Medical Association of Thailand. All rights reserved. Objective: The incidence and outcomes of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are unclear. We evaluated the cumulative in cidence of, risk factors for, and outcomes of ALI/ARDS in surgical ICUs (SICUs). Mater...

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Main Authors: Chaiwat O., Chittawatanarat K., Piriyapathsom A., Pisitsak C., Thawitsri T., Chatmongkolchart S., Kongsayreepong S.
Format: Journal
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85012181029&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/41627
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-416272017-09-28T04:22:23Z Incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: The multicenter thai university-based surgical intensive care unit (THAI-SICU) study Chaiwat O. Chittawatanarat K. Piriyapathsom A. Pisitsak C. Thawitsri T. Chatmongkolchart S. Kongsayreepong S. © 2016, Medical Association of Thailand. All rights reserved. Objective: The incidence and outcomes of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are unclear. We evaluated the cumulative in cidence of, risk factors for, and outcomes of ALI/ARDS in surgical ICUs (SICUs). Material and Method: The multicenter Thai University-based Surgical Intensive Care Unit (THAI-SICU) study was a prospective, observational cohort study including nine university-based SICUs throughout Thailand from April 2011 to January 2013. All > 18-year-old surgical patients who were admitted to general SICUs were recruited. The primary outcome was the incidence of ALI/ARDS. Results: In total, 4,652 patients were analyzed. ALI/ARDS new developed in 114 patients (2.5%). Patients with ALI/ARDS had higher APACHE II (20.0 vs. 11.4, respectively; p < 0.001) and SOFA scores (7.3 vs. 3.1, respectively; p < 0.001) and a higher incidence of past or current smoking (48% vs. 36%, respectively; p < 0.001) than the non-ARDS patients. The 28-day mortality rate was significantly higher in patients with than without ALI/ARDS (50% vs. 12%; p < 0.001). Higher APACHE II and SOFA scores and higher rates of current or past smoking were independent predictors of ALI/ARDS. Conclusion: The incidence of ALI/ARDS in the THAI-SICU study was low, but the mortality rate was high. Higher severity scores and smoking were associated with ALI/ARDS. 2017-09-28T04:22:23Z 2017-09-28T04:22:23Z 2016-09-01 Journal 01252208 2-s2.0-85012181029 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85012181029&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/41627
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description © 2016, Medical Association of Thailand. All rights reserved. Objective: The incidence and outcomes of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are unclear. We evaluated the cumulative in cidence of, risk factors for, and outcomes of ALI/ARDS in surgical ICUs (SICUs). Material and Method: The multicenter Thai University-based Surgical Intensive Care Unit (THAI-SICU) study was a prospective, observational cohort study including nine university-based SICUs throughout Thailand from April 2011 to January 2013. All > 18-year-old surgical patients who were admitted to general SICUs were recruited. The primary outcome was the incidence of ALI/ARDS. Results: In total, 4,652 patients were analyzed. ALI/ARDS new developed in 114 patients (2.5%). Patients with ALI/ARDS had higher APACHE II (20.0 vs. 11.4, respectively; p < 0.001) and SOFA scores (7.3 vs. 3.1, respectively; p < 0.001) and a higher incidence of past or current smoking (48% vs. 36%, respectively; p < 0.001) than the non-ARDS patients. The 28-day mortality rate was significantly higher in patients with than without ALI/ARDS (50% vs. 12%; p < 0.001). Higher APACHE II and SOFA scores and higher rates of current or past smoking were independent predictors of ALI/ARDS. Conclusion: The incidence of ALI/ARDS in the THAI-SICU study was low, but the mortality rate was high. Higher severity scores and smoking were associated with ALI/ARDS.
format Journal
author Chaiwat O.
Chittawatanarat K.
Piriyapathsom A.
Pisitsak C.
Thawitsri T.
Chatmongkolchart S.
Kongsayreepong S.
spellingShingle Chaiwat O.
Chittawatanarat K.
Piriyapathsom A.
Pisitsak C.
Thawitsri T.
Chatmongkolchart S.
Kongsayreepong S.
Incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: The multicenter thai university-based surgical intensive care unit (THAI-SICU) study
author_facet Chaiwat O.
Chittawatanarat K.
Piriyapathsom A.
Pisitsak C.
Thawitsri T.
Chatmongkolchart S.
Kongsayreepong S.
author_sort Chaiwat O.
title Incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: The multicenter thai university-based surgical intensive care unit (THAI-SICU) study
title_short Incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: The multicenter thai university-based surgical intensive care unit (THAI-SICU) study
title_full Incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: The multicenter thai university-based surgical intensive care unit (THAI-SICU) study
title_fullStr Incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: The multicenter thai university-based surgical intensive care unit (THAI-SICU) study
title_full_unstemmed Incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: The multicenter thai university-based surgical intensive care unit (THAI-SICU) study
title_sort incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: the multicenter thai university-based surgical intensive care unit (thai-sicu) study
publishDate 2017
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85012181029&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/41627
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