Fibroblast growth factor 21 (FGF21) therapy attenuates left ventricular dysfunction and metabolic disturbance by improving FGF21 sensitivity, cardiac mitochondrial redox homoeostasis and structural changes in pre-diabetic rats

• Main Authors: Tanajak P., Sa-Nguanmoo P., Wang X., Liang G., Li X., Jiang C., Chattipakorn S., Chattipakorn N.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84979021421&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/41683
• Institution: Chiang Mai University

© 2016 Scandinavian Physiological Society. Published by John Wiley & Sons Ltd Fibroblast growth factor 21 (FGF21) acts as a metabolic regulator and exerts cardioprotective effects. However, the effects of long-term FGF21 administration on the heart under the FGF21-resistant condition in obese,...