Estrogen and DPP4 inhibitor, but not metformin, exert cardioprotection via attenuating cardiac mitochondrial dysfunction in obese insulin-resistant and estrogen-deprived female rats

• Main Authors: Sivasinprasasn S., Sa-Nguanmoo P., Pongkan W., Pratchayasakul W., Chattipakorn S., Chattipakorn N.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84975484640&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/41711
• Institution: Chiang Mai University

© 2016 by The North American Menopause Society. Objective: Cardiac function was markedly compromised in obese insulin-resistant and estrogen-deprived rats. Metformin and dipeptidyl peptidase-4 inhibitor (vildagliptin) were reported to improve cardiac function in insulinresistant rats. Their effects...