Acute bone infarction: a rare complication in thalassemia

© 2016, ISS. Acute bone infarction is a well-described complication in sickle cell hemoglobinopathy but it is rarely reported in patients with thalassemia. This report describes an 18-year-old man with homozygous β-thalassemia presenting with a fever and severe acute bilateral ankle pain. The acute...

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Main Authors:	Kanthawang T., Pattamapaspong N., Louthrenoo W.
Format:	Journal
Published:	2017
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84964199973&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/41734
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Institution:	Chiang Mai University

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spelling	th-cmuir.6653943832-417342017-09-28T04:23:05Z Acute bone infarction: a rare complication in thalassemia Kanthawang T. Pattamapaspong N. Louthrenoo W. © 2016, ISS. Acute bone infarction is a well-described complication in sickle cell hemoglobinopathy but it is rarely reported in patients with thalassemia. This report describes an 18-year-old man with homozygous β-thalassemia presenting with a fever and severe acute bilateral ankle pain. The acute onset of severe pain and fever were clinical mimics of infectious arthritis and osteomyelitis. Magnetic resonance imaging revealed acute bone infarction in the meta-diaphysis of bilateral tibias presenting as central unenhanced devitalized bone with T1-high signal intensity fluid in the subperiosteum and soft tissue. Characteristic imaging features are discussed, emphasizing the benefit of fat suppression pre-and post-intravenous gadolinium T1-weighted images. The etiologies of bone infarction in thalassemia are reviewed. 2017-09-28T04:23:05Z 2017-09-28T04:23:05Z 2016-07-01 Journal 03642348 2-s2.0-84964199973 10.1007/s00256-016-2387-6 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84964199973&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/41734
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
description	© 2016, ISS. Acute bone infarction is a well-described complication in sickle cell hemoglobinopathy but it is rarely reported in patients with thalassemia. This report describes an 18-year-old man with homozygous β-thalassemia presenting with a fever and severe acute bilateral ankle pain. The acute onset of severe pain and fever were clinical mimics of infectious arthritis and osteomyelitis. Magnetic resonance imaging revealed acute bone infarction in the meta-diaphysis of bilateral tibias presenting as central unenhanced devitalized bone with T1-high signal intensity fluid in the subperiosteum and soft tissue. Characteristic imaging features are discussed, emphasizing the benefit of fat suppression pre-and post-intravenous gadolinium T1-weighted images. The etiologies of bone infarction in thalassemia are reviewed.
format	Journal
author	Kanthawang T. Pattamapaspong N. Louthrenoo W.
spellingShingle	Kanthawang T. Pattamapaspong N. Louthrenoo W. Acute bone infarction: a rare complication in thalassemia
author_facet	Kanthawang T. Pattamapaspong N. Louthrenoo W.
author_sort	Kanthawang T.
title	Acute bone infarction: a rare complication in thalassemia
title_short	Acute bone infarction: a rare complication in thalassemia
title_full	Acute bone infarction: a rare complication in thalassemia
title_fullStr	Acute bone infarction: a rare complication in thalassemia
title_full_unstemmed	Acute bone infarction: a rare complication in thalassemia
title_sort	acute bone infarction: a rare complication in thalassemia
publishDate	2017
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84964199973&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/41734
_version_	1681422056842854400

Acute bone infarction: a rare complication in thalassemia

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