Helical tomotherapy optimized planning parameters for nasopharyngeal cancer

© Published under licence by IOP Publishing Ltd. Helical TomoTherapy(HT) planning depends on optimize parameters including field width (FW), pitch factor (PF) and modulation factor (MF). These optimize parameters are effect to quality of plans and treatment time. The aim of this study was to find th...

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Main Authors: Yawichai K., Chitapanarux I., Wanwilairat S.
Format: Journal
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84971632016&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42011
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spelling th-cmuir.6653943832-420112017-09-28T04:24:46Z Helical tomotherapy optimized planning parameters for nasopharyngeal cancer Yawichai K. Chitapanarux I. Wanwilairat S. © Published under licence by IOP Publishing Ltd. Helical TomoTherapy(HT) planning depends on optimize parameters including field width (FW), pitch factor (PF) and modulation factor (MF). These optimize parameters are effect to quality of plans and treatment time. The aim of this study was to find the optimized parameters which compromise between plan quality and treatment times. Six nasopharyngeal cancer patients were used. For each patient data set, 18 treatment plans consisted of different optimize parameters combination (FW=5.0, 2.5, 1.0 cm; PF=0.43, 0.287, 0.215; MF2.0, 3.0) were created. The identical optimization procedure followed ICRU83 recommendations. The average D50 of both parotid glands and treatment times per fraction were compared for all plans. The study show treatment plan with FW1.0 cm showed the lowest average D50 of both parotid glands. The treatment time increased inversely to FW. The FW1.0 cm the average treatment time was 4 times longer than FW5.0 cm. PF was very little influence on the average D50 of both parotid glands. Finally, MF increased from 2.0 to 3.0 the average D50 of both parotid glands was slightly decreased. However, the average treatment time was increased 22.28%. For routine nasopharyngeal cancer patients with HT, we suggest the planning optimization parameters consist of FW=5.0 cm, PF=0.43 and MF=2.0. 2017-09-28T04:24:46Z 2017-09-28T04:24:46Z 2016-03-24 Journal 17426588 2-s2.0-84971632016 10.1088/1742-6596/694/1/012002 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84971632016&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42011
institution Chiang Mai University
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country Thailand
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description © Published under licence by IOP Publishing Ltd. Helical TomoTherapy(HT) planning depends on optimize parameters including field width (FW), pitch factor (PF) and modulation factor (MF). These optimize parameters are effect to quality of plans and treatment time. The aim of this study was to find the optimized parameters which compromise between plan quality and treatment times. Six nasopharyngeal cancer patients were used. For each patient data set, 18 treatment plans consisted of different optimize parameters combination (FW=5.0, 2.5, 1.0 cm; PF=0.43, 0.287, 0.215; MF2.0, 3.0) were created. The identical optimization procedure followed ICRU83 recommendations. The average D50 of both parotid glands and treatment times per fraction were compared for all plans. The study show treatment plan with FW1.0 cm showed the lowest average D50 of both parotid glands. The treatment time increased inversely to FW. The FW1.0 cm the average treatment time was 4 times longer than FW5.0 cm. PF was very little influence on the average D50 of both parotid glands. Finally, MF increased from 2.0 to 3.0 the average D50 of both parotid glands was slightly decreased. However, the average treatment time was increased 22.28%. For routine nasopharyngeal cancer patients with HT, we suggest the planning optimization parameters consist of FW=5.0 cm, PF=0.43 and MF=2.0.
format Journal
author Yawichai K.
Chitapanarux I.
Wanwilairat S.
spellingShingle Yawichai K.
Chitapanarux I.
Wanwilairat S.
Helical tomotherapy optimized planning parameters for nasopharyngeal cancer
author_facet Yawichai K.
Chitapanarux I.
Wanwilairat S.
author_sort Yawichai K.
title Helical tomotherapy optimized planning parameters for nasopharyngeal cancer
title_short Helical tomotherapy optimized planning parameters for nasopharyngeal cancer
title_full Helical tomotherapy optimized planning parameters for nasopharyngeal cancer
title_fullStr Helical tomotherapy optimized planning parameters for nasopharyngeal cancer
title_full_unstemmed Helical tomotherapy optimized planning parameters for nasopharyngeal cancer
title_sort helical tomotherapy optimized planning parameters for nasopharyngeal cancer
publishDate 2017
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84971632016&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42011
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