Dysregulation of ferroportin gene expression in β⁰-thalassemia/Hb E disease

• Main Authors: Sornjai W., Jaratsittisin J., Khungwanmaythawee K., Svasti S., Fucharoen S., Lithanatudom P., Smith D.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84957439403&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/42108
• Institution: Chiang Mai University

© 2015, Springer-Verlag Berlin Heidelberg. During erythropoiesis, iron levels need to be carefully regulated to ensure there is sufficient iron available for hemoglobin synthesis, but that there is no excess to cause damage to the developing erythroblast. Iron influx to the developing erythroblast i...