A new cytotoxic clerodane diterpene from casearia graveolens twigs

The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 show...

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Main Authors: Meesakul P., Ritthiwigrom T., Cheenpracha S., Sripisut T., Maneerat W., MacHan T., Laphookhieo S.
Format: Journal
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84973408865&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42144
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Institution: Chiang Mai University
id th-cmuir.6653943832-42144
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spelling th-cmuir.6653943832-421442017-09-28T04:25:27Z A new cytotoxic clerodane diterpene from casearia graveolens twigs Meesakul P. Ritthiwigrom T. Cheenpracha S. Sripisut T. Maneerat W. MacHan T. Laphookhieo S. The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 showed strong cytotoxicity against oral cavity and breast cancer cell lines with IC50 values of 2.48 and 6.63 ìM, respectively. 2017-09-28T04:25:27Z 2017-09-28T04:25:27Z 2016-01-23 Journal 1934578X 2-s2.0-84973408865 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84973408865&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42144
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 showed strong cytotoxicity against oral cavity and breast cancer cell lines with IC50 values of 2.48 and 6.63 ìM, respectively.
format Journal
author Meesakul P.
Ritthiwigrom T.
Cheenpracha S.
Sripisut T.
Maneerat W.
MacHan T.
Laphookhieo S.
spellingShingle Meesakul P.
Ritthiwigrom T.
Cheenpracha S.
Sripisut T.
Maneerat W.
MacHan T.
Laphookhieo S.
A new cytotoxic clerodane diterpene from casearia graveolens twigs
author_facet Meesakul P.
Ritthiwigrom T.
Cheenpracha S.
Sripisut T.
Maneerat W.
MacHan T.
Laphookhieo S.
author_sort Meesakul P.
title A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_short A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_full A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_fullStr A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_full_unstemmed A new cytotoxic clerodane diterpene from casearia graveolens twigs
title_sort new cytotoxic clerodane diterpene from casearia graveolens twigs
publishDate 2017
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84973408865&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42144
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